Are you a take flight or fight type of person?
Sometimes I tend to take flight since I'm bashful and I've actually had people grab onto my arm so I don't get away during the conversation! :scared:
A lot depends on the circumstances. Usually I prefer to avoid an outright confrontation but in a situation where, for whatever reason, I figure that "fight" is the best option I usually look to end it as fast as possible. In my teenage years I did karate and my instructor always said that it's best not to fight at all but if you do have to fight you need to take someone down and make sure they don't get up again for a while - if they get up before you've got away they're still going to have the same issue as before but now they'll be angry as well.
Truth be told if I were in a situation where I had to protect my wife from some form of danger I'd be more likely to make a stand and fight with whatever it took, not least because it's no good running away unless I can be sure she's also going to escape.
ETA: As a rule I don't feel threatened in most situations, my biggest concern is wild animals when out hiking. That's why I carry a big knife in the woods