Cure for the Coronavirus Pandemic

[hobie]

Here is a cure that they are finding for the worst cases, those really having issues trying to breath. Anyone know what makes it effective?

Chloroquine to be tested for coronavirus treatment in the US
The President of the United States, Donald Trump, announced on 19 March that chloroquine (hydroxychloroquine/Plaquenil), a drug used to treat malaria and arthritis, was approved by the US Food and Drug Administration (FDA) to be tested as a treatment for COVID-19. Chloroquine is being tested in various clinical trials conducted by government agencies and academic institutions.

Coronavirus outbreak: Top coronavirus drugs and vaccines in development

Coronavirus drugs: Here are five major coronavirus vaccines and drugs being developed for the treatment of Wuhan coronavirus. coronavirus medicine; corona virus cure; coronavirus cure update, coronavirus cure, coronavirus vaccine update, cure for coronavirus, coronavirus treatment update

www.clinicaltrialsarena.com

 

[tango]

No idea why it would work but interesting to see it being used to treat two very different conditions already.

 

[hedrick]

Please don't confuse "being tested" with "a cure."

It is an anti-viral. For some viruses it inhibits their reproduction. Whether that's true in this case is still under study. According to Wikipedia, it is contraindicated for people with diabetes and heart disease. Since those are the most at risk for COVID-19, it's an obvious limitation.

 

[tango]

Please don't confuse "being tested" with "a cure."

It is an anti-viral. For some viruses it inhibits their reproduction. Whether that's true in this case is still under study. According to Wikipedia, it is contraindicated for people with diabetes and heart disease. Since those are the most at risk for COVID-19, it's an obvious limitation.

Certainly that would be a limitation but if it works (stressing the IF there) it could be useful to help protect the elderly population.

 

[hobie]

Please don't confuse "being tested" with "a cure."

It is an anti-viral. For some viruses it inhibits their reproduction. Whether that's true in this case is still under study. According to Wikipedia, it is contraindicated for people with diabetes and heart disease. Since those are the most at risk for COVID-19, it's an obvious limitation.

Whoa! That's not good news for me, as I am working on both of those issues....
But it does work, so if you are at the hospital with severe symptoms, talk to your doctor or health professional about it.

 

[bharath]

I am daily searching for this thing, unfortunately their is no vaccine till now and they were still yet to be tested. I am hoping soon the vaccine will arrive to kill the virus everywhere.
UK Scientists are working for a vaccine.

Coronavirus Vaccine: Oxford university begins enrolling over 500 volunteers for coronavirus vaccine trial | World News - Times of India

UK News: Scientists from the University of Oxford have opened up their COVID-19 vaccines for clinical trial recruitments as part of a “rapid vaccine response”

timesofindia.indiatimes.com

 

[hedrick]

There are several phase 1 trials. Unfortunately it's still at least a year away. Phase 1 trials just make sure that the vaccine doesn't hurt anyone. They don't determine that it works.

 

[tango]

There are several phase 1 trials. Unfortunately it's still at least a year away. Phase 1 trials just make sure that the vaccine doesn't hurt anyone. They don't determine that it works.

Perhaps in a strict sense but I don't imagine they would bother testing something unless at least some laboratory tests indicated that it could work, subject to safety testing.

 

[bharath]

There are several phase 1 trials. Unfortunately it's still at least a year away. Phase 1 trials just make sure that the vaccine doesn't hurt anyone. They don't determine that it works.

Life is too short so we have achieve atleast what we can do. The vaccine should be tested for this dangerous disease and giving time elapsing is a worse. I am hoping soon someone will come up with something in April to stop this Chinese Virus.

 

[hedrick]

Life is too short so we have achieve atleast what we can do. The vaccine should be tested for this dangerous disease and giving time elapsing is a worse. I am hoping soon someone will come up with something in April to stop this Chinese Virus.

Not a vaccine, but there are a few treatments that look promising. End of April seems possible.

 

[tango]

U.S. could face 200,000 coronavirus deaths, millions of cases, Fauci warns

This article shows Dr Fauci suggesting that the US could see "from 100,000 to 200,000 deaths" from this virus. That's more than the seasonal flu, which annually claims 12,000 - 60,000 lives according to the article, but this is still a huge improvement from previous projections that were talking about death tolls from 1-2 million and maybe more.

 

[Lamb]

U.S. could face 200,000 coronavirus deaths, millions of cases, Fauci warns

This article shows Dr Fauci suggesting that the US could see "from 100,000 to 200,000 deaths" from this virus. That's more than the seasonal flu, which annually claims 12,000 - 60,000 lives according to the article, but this is still a huge improvement from previous projections that were talking about death tolls from 1-2 million and maybe more.

He also said, "Don't hold me to this" after stating the numbers. That's the part that the media is leaving out of their quotes and I only know this because I saw the video.

 

[hedrick]

1-2 million was before the current distancing. Currently 100K seems a reasonable projection. But you can't compare it with flu because we're doing lots of things to control it that we don't do for flu.

 

[tango]

He also said, "Don't hold me to this" after stating the numbers. That's the part that the media is leaving out of their quotes and I only know this because I saw the video.

I'd say that sort of proviso was pretty much implied. There's still a huge difference between "the sky is falling" estimates of millions of deaths and 200,000.

I can't speak for Dr Fauci but I'd imagine someone in his position wouldn't suggest numbers, even with provisos, unless he had at least some confidence in what he was saying. Of course any model is only as good as the assumptions, as any modeller worth their salt will say.

 

[tango]

1-2 million was before the current distancing. Currently 100K seems a reasonable projection. But you can't compare it with flu because we're doing lots of things to control it that we don't do for flu.

The point is that 100,000 deaths isn't so far off the top end of what seasonal flu inflicts, not that this is "just like the flu".

On what basis do you say that 100k seems like a reasonable projection? Are you familiar with modelling epidemics? (Serious question, I don't know you or your areas of expertise)

 

[hedrick]

I'm not a modeler. I'm an IT manager. The President is using models from the University of Washington. They're available at http://covid19.healthdata.org/. I've read many news stories describing different expert opinions. Based on that, I think this site is on the optimistic side. It projects a bit under 100K. The President is now saying 100 - 200K. That sounds like the range of predictions I've seen in various news stories.

100K is in fact a bit worse than a bad flu season. But remember, that's after doing huge amounts of work to contain it. Furthermore, what worries NY isn't just the deaths, but the fact that it overwhelms their hospitals. The site has a pulldown that lets you choose a state. Take a look at NY, and see how much it exceeds their capacity. They seem to be the worst case.

 

[Lamb]

I'm not a modeler. I'm an IT manager. The President is using models from the University of Washington. They're available at http://covid19.healthdata.org/. I've read many news stories describing different expert opinions. Based on that, I think this site is on the optimistic side. It projects a bit under 100K. The President is no
w saying 100 - 200K. That sounds like the range of predictions I've seen in various news stories.

100K is in fact a bit worse than a bad flu season. But remember, that's after doing huge amounts of work to contain it. Furthermore, what worries NY isn't just the deaths, but the fact that it overwhelms their hospitals. The site has a pulldown that lets you choose a state. Take a look at NY, and see how much it exceeds their capacity. They seem to be the worst case.

If only New York had taken things more seriously instead of Cuomo encouraging people to go about their normal lives and go out and about while other states were on lock down...the hospitals wouldn't be so overwhelmed. The state I live in says they aren't overwhelmed yet and they have a high number of cases throughout the state. Maybe we're just more prepared than NY?

 

[tango]

I'm not a modeler. I'm an IT manager. The President is using models from the University of Washington. They're available at http://covid19.healthdata.org/. I've read many news stories describing different expert opinions. Based on that, I think this site is on the optimistic side. It projects a bit under 100K. The President is now saying 100 - 200K. That sounds like the range of predictions I've seen in various news stories.

100K is in fact a bit worse than a bad flu season. But remember, that's after doing huge amounts of work to contain it. Furthermore, what worries NY isn't just the deaths, but the fact that it overwhelms their hospitals. The site has a pulldown that lets you choose a state. Take a look at NY, and see how much it exceeds their capacity. They seem to be the worst case.

Sure, I appreciate that maintaining physical distance from people will have made a huge difference. It's hardly surprising that a city with so many people packed into a tiny space is about as good as it gets from the perspective of a virus. Maintaining physical separation when you've got that many people in that small a space is all but impossible.

ETA: I have a couple of friends with far more medical expertise than I do. The conclusion I've drawn from talking to them is that this is potentially very serious but the main problem with it is that it's unknown and we don't (yet) have a vaccine for it.

 

[hobie]

Well looks like they are trying it out, lets hope for the best...
CORONAVIRUS

"FDA issues emergency authorization of anti-malaria drug for coronavirus care"
https://www.politico.com/news/2020/03/29/fda-emergency-authorization-anti-malaria-drug-155095

"Anti-malaria drug helps speed up recovery of coronavirus patients: study

https://nypost.com/2020/04/02/antimalaria-drug-speeds-up-recovery-of-coronavirus-patients-study/

 

[Lamb]

No one wanted to admit Trump was right so they were fighting it as much as they could.